Dr Matthew Raybould
Postdoctoral Researcher at the University of Oxford, working in the Oxford Protein Informatics Group (OPIG).
Research Interests: I am fascinated by the adaptive immune system and am driven to understand the efficiency of the naive/baseline repertoire, whose relatively sparse diversity can instigate immune responses against almost any antigen. We aim to harness the growing body of repertoire sequencing data to elucidate core principles governing B cell/T cell selection and response across populations. Our belief is that combining genetic information (clonality), amino acid chemistry, and structural information (binding site topography) will yield exciting discoveries that can contribute to the fields of immunodiagnostics, immunosenescence, immunodeficiency/autoimmunity, allergy, and nature-inspired immunotherapeutic/vaccine design.
